Carpometacarpal Joint Injection
Other Names
- CMC Joint Injection
- Thumb CMC Joint Injection
- CMCJ Injection
- First carpometacarpal joint injection
Background

Key Points
- This page refers to injection of the Carpometacarpal Joint of the thumb
- This injection can be performed with or without ultrasound, although we recommend ultrasound
- Use a 25 gauge, 1.5 inch needle
- Transducer: high frequency linear array
- Dorsal approach is optimal
- Be careful to avoid the neurovascular bundle
Anatomy of the Carpometacarpal Joint
- Thumb CMC Joint
- Also called the trapeziometacarpal joint
- Characterized by the articular of the 1st Metacarpal and Trapezium
- Radial artery and radial nerve run along the volar surface
- Abductor pollicis longus, extensor pollicis brevis run along the radial side
- Anatomic snuff box
- Radial: APL, EPB
- Dorsal: ECR, EPL
- Floor: Trapezium
- Anterior: 1st metacarpal
Palpation Guidance vs Ultrasound Guidance
- Smith et al found palpation guided injections were 80% accurate while ultrasound guided injections were 100% accurate[2]
- Derian et al, using a novel assessment scale, found no difference between ultrasound and palpation guidance in a cadaveric study[3]
- Philip et al found palpation guidance had an accuracy of only 63%, that ultrasound improved accuracy but this was dependent on user experience[4]
- Katt et al found palpation guidance to be only 80% accurate[5]
Indications
Contraindications
- Absolute
- Anaphylaxis to injectates
- Overlying cellulitis, skin lesion or systemic infection
- Relative
- Can be treated with less invasive means
- Hyperglycemia or poorly controlled diabetes
- Lack of symptom improvement with previous injection
Procedure






Equipment
- Sterile including chloraprep, chlorhexadine, iodine
- Gloves
- Needle: typically 25 to 27 gauge, 0.5 to 1.0 inch
- Syringe: 1-3 mL
- Gauze
- Ethyl Chloride
- Bandage
- Injectate
- Local anesthetic
- Corticosteroid
Ultrasound Findings
- Use a high frequency, linear probe
- Common findings:
- Enlarged triangular joint space
- Cortical irregularities
- Erosions seen in inflammatory arthropathies
- Effusion
Technique: Palpation Guided
- Patient Position
- The patient should be seated, alternatively they can be supine
- Hand should be resting on the examination table
- Radial side is up or superior, ulnar side resting on the table
- Needle Orientation and Approach
- Proximal to distal
- Description
- Palpate the small space between the trapezium and first metacarpal dorsally
- Use the anatomic snuffbox for medial and lateral borders
- Between the 1st and 2nd dorsal compartment
- Mark this space with a pen or other blunt object
- Sterilize the marked skin
- Inject the needle into the joint space
- Angle should be about 45° degrees to the skin
- You should feel it "drop in" to the space
- You may have to redirect cranial or caudal in small increments to achieve this
- Pearls and Pitfalls
- An assistant or the proceduralist should apply traction on the distal thumb to further open the joint space
- Aspirate to make sure you aren't in a vessel prior to injection
Ultrasound Guided In-Plane
- Patient position
- Patient is seated or supine
- Hand placed on table with ulnar sidse down, radial side up
- Transducer position
- Over the anatomic snuff box
- Aligned with the long axis of the carpometacarpal joint
- Needle Orientation and Approach
- In Plane
- Stand off oblique technique
- Target
- CMC joint space
- Pearls and Pitfalls
- Be careful to avoid the neurovascular bundle
- Joint space is characterized by the "seagull" appearance of the carpal and metacarpal reflection
Ultrasound Guided Out-of-Plane
- Patient position
- Patient is seated or supine
- Hand placed on table with ulnar sidse down, radial side up
- Transducer position
- Over the anatomic snuff box
- Aligned with the long axis of the carpometacarpal joint
- Needle Orientation and Approach
- Out of Plane
- Step-wise technique
- Target
- CMC joint space
- Pearls and Pitfalls
- See above
Aftercare
- No significant restrictions
- Can augment with ice, NSAIDS
- Consider placement in a Thumb Spica Splint
Complications
- Skin: Subcutaneus fat atrophy, skin atrophy, skin depigmentation
- Painful local reaction
- Infection
- Hyperglycmia
- Tendon, nerve or blood vessel injury
See Also
References
- ↑ Vos, F. M., et al. "A statistical shape model without using landmarks." Proceedings of the 17th International Conference on Pattern Recognition, 2004. ICPR 2004.. Vol. 3. IEEE, 2004.
- ↑ Smith, Jay, et al. "Accuracy of sonographically guided and palpation guided scaphotrapeziotrapezoid joint injections." Journal of Ultrasound in Medicine 30.11 (2011): 1509-1515.
- ↑ Derian, Armen, et al. "Accuracy of ultrasound-guided versus palpation-based carpometacarpal joint injections: a randomized pilot study in cadavers." Ultrasound 26.4 (2018): 245-250.
- ↑ To, Philip, et al. "The accuracy of common hand injections with and without ultrasound: an anatomical study." Hand 12.6 (2017): 591-596.
- ↑ Katt, Brian M., et al. "The efficacy of intra-articular versus extra-articular corticosteroid injections in the thumb carpometacarpal joint." Journal of Hand Surgery Global Online 4.3 (2022): 128-134.
- ↑ Image courtesy of rheumatologynework.com, "injection of first carpometacarpal joint"
- ↑ 7.0 7.1 7.2 7.3 Malanga, Gerard, and Kenneth Mautner. Atlas of ultrasound-guided musculoskeletal injections. McGraw-Hill, 2014.
- ↑ Flores, Dyan V., Marcos Loreto Sampaio, and Aakanksha Agarwal. "Ultrasound-guided injection and aspiration of small joints: Techniques, pearls, and pitfalls." Skeletal Radiology 53.2 (2024): 195-208.
Created by:
John Kiel on 18 October 2022 17:00:51
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Last edited:
19 August 2025 18:27:02
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