Intersection Syndrome
Other Names
- Tenosynovitis of first and second dorsal compartment
- Tenosynovitis of first and second extensor compartment
- Oarsmen's wrist
- Crossover syndrome
- Squeaker's wrist
- Abductor pollicis longus bursitis
- Abductor pollicis longus syndrome
- Subcutaneous polymyositis
- Peritendinitis crepitans
- Bugaboo forearm
- Intersection Syndrome of the Forearm
- Proximal Intersection Syndrome
Background
- This page refers to intersection syndrome, a syndrome characterized by the point at which the 1st Dorsal Compartment of the Wrist and 2nd Dorsal Compartment of the Wrist intersect
History
- First described in the literature by Alfred-Armand-Louis-Marie Velpeau, a French anatomist and surgeon, in 1841 (need citation)
- Term 'intersection syndrome' first coined by James H. Dobyns in 1978 at the Mayo Clinic (need citation)
Epidemiology
- Estimated to be less than 1 per 100,000 per year (need citation)


Introduction
General
- Characterized by an inflammatory tenosynovitis at the intersection of the 1st and 2nd dorsal compartment
- Pain is located over the dorsoradial forearm, made worse with resisted wrist extension and thumb extension
- The term 'intersection syndrome' refers to intersection of the musculotendinous junctions of the 1st and 2nd dorsal compartment tendons[3]
- Relatively uncommon, often misdiagnosed as De Quervains Tenosynovitis
Etiology
- Result of repetitive extension and flexion activities
- Friction injury at crossover of two junctions leads to inflammation and subsequent tenosynovitis
Anatomy of the 1st and 2nd Extensor Tendon Compartments
- 1st extensor compartment: Abductor Pollicis Longus, Extensor Pollicis Brevis
- 2nd extensor compartment: Extensor Carpi Radialis Longus, Extensor Carpi Radialis Brevis
- Intersection
- The 1st dorsal compartment crosses over the 2nd dorsal compartment just proximal to the extensor retinaculum and radial styloid
- Also characterized to be 4 - 6 cm proximal to Lister's tubercle
- Angle at intersection is approximately 60°
Risk Factors
- Sports[4]
- Rowing
- Canoeing
- Skiing
- Racquet sports
- Horseback riding
- Weight lifters
Differential Diagnosis
Differential Diagnosis Intersection Syndrome
- Wartenbergs Syndrome
- De Quervains Tenosynovitis
- Muscle Strain
- Thumb CMC Arthritis
- Extensor Pollicis Longus Tendinitis
- Extensor digitorum tenosynovitis
- Drummer’s wrist
Differential Diagnosis Wrist Pain
- Fractures
- Dislocations
- Wrist Dislocation (Radiocarpal and/or Ulnocarpal)
- Carpometacarpal Joint Dislocation
- Distal Radioulnar Joint Dislocation
- Lunate Dislocation
- Perilunate Dislocation
- Instability & Degenerative
- Tendinopathies & Ligaments
- Neuropathies
- Pediatric Considerations
- Distal Radial Epiphysitis (Gymnast's Wrist)
- Torus Fracture
- Arthropathies
- Cartilage
- Vascular
- Other
Differential Diagnosis Forearm Pain
- Fractures
- Pediatric Specific Fractures
- Dislocations & Instability
- Soft Tissue Trauma
- Tendinopathies
- Neuropathies
- Pediatric Considerations
Clinical Features

History
- Patients will endorse pain approximately 4-6 cm proximal and dorsal to listers tubercle
Physical Exam: Physical Exam Forearm
- Tenderness over the dorsoradial forearm (5 cm proximal to listers tubercle)
- Swelling and crepitus may be appreciated on exam
- Worse with wrist and thumb extension
- Crepitus is specific to intersection syndrome
- Pronation is typically more painful than supination
Special Tests
- Crepitus over area with resisted wrist extension, thumb extension
- Finkelstein Test: may be positive, but requires more provocation than De Quervain's
Evaluation


- Primarily a clinical diagnosis based on history and physical exam
Radiographs
- Standard Radiograms Forearm, Standard Radiographs Wrist
- Useful for excluding other pathology
- Typically normal
Ultrasound
- Point of care ultrasound can aid in diagnosis
- Findings
- Hypoechoic area in between the two dorsal compartments
- Thickening of the tendon sheaths
- Subcutaneous edema
- Ganglion cyst
CT
- Not helpful in the diagnosis of intersection syndrome
MRI
- Gold standard to confirm diagnosis
- Findings
- Demonstrates peritendinous edema around 1st and 2nd extensor compartments[7]
- Chronic cases may show a stenosing tenosynovitis
- Muscle edema
- Tendon thickening
- Loss of normal comma shape of the tendon
- Juxtacortical edema
Classification
- N/A
Management
Nonoperative
- Most cases can successfully be managed conservatively
- Medications
- NSAIDS
- Acetaminophen
- Topical medications
- Relative rest from offending activity or sport
- Ice, especially if swelling is present
- Splinting
- Cock Up Wrist Splint or other pre-fabricated splint
- Physical Therapy
- No evidence based protocol
- Consider eccentric strengthening, soft tissue manipulation, stretching
- CSI: Intersection Syndrome of the First and Second Dorsal Compartments Injection
- Should be performed under ultrasound guidance
Operative
- Indications
- Rarely necessary for recalcitrant cases
- Technique
- Surgical debridement and release
Rehab and Return to Play
Rehabilitation
- Modification of offending/ sporting activities
Return to Play/ Work
- Relative rest for athletes
- Graded return to play as they progress through therapy
Prognosis and Complications
- Chronic pain
See Also
Internal
External
References
- ↑ Image courtesy of Malanga, Gerard A., and Kenneth R. Mautner. "Atlas of ultrasound-guided musculoskeletal injections." (No Title) (2014).
- ↑ 2.0 2.1 Skinner, Thomas M. "Intersection syndrome: the subtle squeak of an overused wrist." The Journal of the American Board of Family Medicine 30.4 (2017): 547-551.
- ↑ Lee RP, Hatem SF, Recht MP. Extended MRI findings of intersection syndrome. Skeletal Radiol. 2009;38 (2): 157-63. doi:10.1007/s00256-008-0587-4
- ↑ Browne J, Helms CA. Intersection syndrome of the forearm. Arthritis Rheum. 2006 Jun;54(6):2038.
- ↑ Case courtesy of Roberto Schubert, Radiopaedia.org, rID: 24709
- ↑ Case courtesy of Maulik S Patel, Radiopaedia.org, rID: 66323
- ↑ Costa CR, Morrison WB, Carrino JA. MRI features of intersection syndrome of the forearm. AJR Am J Roentgenol. 2003 Nov;181(5):1245-9.
Created by:
John Kiel on 18 June 2019 23:15:09
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Last edited:
4 August 2024 23:40:58
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