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Hutchinson Pupil

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Other Names

Hutchinson Pupil

Hutchinson Pupil[1]
Hutchinson pupil in a patient with a migraine disorder[2]
  • Hutchinson pupil
  • Hutchinson's pupil
  • Unilateral fixed dilated pupil
  • Ipsilateral fixed dilated pupil
  • Third cranial nerve compression pupil
  • Oculomotor nerve compression pupil
  • Herniation pupil

Purpose

  • Clinical exam finding that suggests life-threatening intracranial pathology
  • Identify compression of the ipsilateral oculomotor nerve (cranial nerve III)
  • Most classically this is due to pending or established uncal herniation, although the differential is much broader

Description

  • Perform normal pupillary eye exam
  • Normally, pupils are equal, round and reactive to lighht and accomodate
  • Hutchinson's pupil
    • Unilateral, dilated, poorly reactive or non-reactive pupil
    • Can eventually assume a "down and out" position due to complete third nerve palsy
    • Occurs ipsilateral to lesion

Pathology

  • Intracranial Herniation
    • Uncal herniation (classic cause)
    • Transtentorial herniation
    • Increased intracranial pressure
  • Traumatic Brain Injury
    • Epidural hematoma
    • Subdural hematoma
    • Cerebral contusion
    • Diffuse cerebral edema
  • Cerebrovascular Disease
    • Intracerebral hemorrhage
    • Massive ischemic stroke with cerebral edema
    • Hemorrhagic transformation
  • Intracranial Mass Lesions
    • Brain tumors
    • Brain abscess
    • Metastatic lesions
    • Large arachnoid cyst
  • Vascular Disorders
    • Posterior communicating artery aneurysm causing third nerve compression
    • Cavernous sinus lesions
  • Other Causes
    • Severe cerebral edema
    • Postoperative intracranial swelling
    • Brain infections causing mass effect

Evidence

  • Unknown

See Also


References

  1. Penney, Dawn C., Zoë M. Rushetsky, and Donald W. Penney. "Abnormal pupils at the bedside: rapid recognition of neurologic and systemic emergencies in acute care settings." International Journal of Emergency Medicine 19.1 (2026): 73.
  2. Skeik, Nedaa, and Fadi I. Jabr. "Migraine with benign episodic unilateral mydriasis." International Journal of General Medicine (2011): 501-503.
Created by:
John Kiel on 30 June 2026 19:05:39
Authors:
Last edited:
1 July 2026 02:50:02
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