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Spinal Cord

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Description

Anatomy of the spinal cord[1]
Ventral view and transverse section through spinal cord and spinal nerve with endoneurium and perineurium and epineurium[2]
Lateral view of spinal cord topography and its different regions: cervical district (C1 to C8)), Thoracic district (T1 to T 12), Lumbar district (L1 to L5), Sacral district (S1 to S5) and Coccygeal segment. Each segment of the spinal cord directly innervates specific regions of skin and muscle districts[3]

General

  • Tubular bundle of nervous tissue extending from the brainstem to the lumbar vertebrae
  • When combined with the brain, forms the central nervous system

Gross Anatomy

  • Cylindrical structure, grey-white in color
  • Arises as a continuation of the medulla (inferior part of the brain stem))
  • Travels inferiorly within the vertebral canal
  • Protected/ surrounded by meninges which contain cerebrospinal fluid
  • At approximately L2, the cord tapers off forming conus medullaris
  • The spinal nerves bundled together at the end of the conus are known as cauda equina
  • Cervical enlargement: located at C4-T1, represents origin of brachial plexus
  • Lumbar enlargement: located at T11-L1, represents origin of lumbosacral plexus

Spinal Meninges

  • Three membranes that surround the spinal cord
  • Function: contain cerebrospinal fluid, support and protect the spinal cord
  • Dura mater: most external of the meninges
  • Arachnoid mater: middle layer
  • Pia Mater: innermost layer

Formation of Spinal Nerves

  • Mixed nerves that originate from the spinal cord, forming the peripheral nervous system
  • Each nerve begins as a anterior/motor and posterior/sensory nerve root
  • They coalesce at the intervertebral foramina forming a single spinal nerve unit
  • When they exit the intervertebral foramina, they divide into two rami
    • Posterior rami: nerve fibers to the synovial joints of the vertebral column, deep muscles of the back, and the overlying skin
    • Anterior rami: nerve fibers to much of the remaining area of the body, both motor and sensory

Vasculature

  • Anterior spinal artery formed by branches of the vertebral arteries
  • Posterior spinal arteries originate from the posteroinferior cerebellar and vertebral arteries
  • Artery of Adamkiewicz supplies inferior 2/3 of the spinal cord
  • Venous drainage is through three anterior/posterior spinal veins

See Also


References

  1. II, Phillip A. Swanson, and Dorian B. McGavern. "Portals of viral entry into the central nervous system." The blood-brain barrier in health and disease, Volume two: Pathophysiology and pathology 23 (2015).
  2. Kraan, Gerardus Arnoldus. "The extraforaminal ligaments of the human spinal nerves. Anatomical and Biomechanical study." (2012).
  3. Facchin, Marco, Marco Viola, and Elia Zanin. "Retiring the “Cinderella view”: the spinal cord as an intrabodily cognitive extension." Biology & Philosophy 36.5 (2021): 45.
Created by:
John Kiel on 15 March 2025 15:01:05
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Last edited:
15 March 2025 15:13:49
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