Medial Plica Syndrome
(Redirected from Plica Syndrome)
Other Names
- Synovial Plica Syndrome (SPS)
- Medial Plica Syndrome
- Medial Plica Shelf Syndrome
- Plica Syndrome
- Knee Plica Syndrome
- Medial Synovial Plica Syndrome
- Pathologic Plica
- Symptomatic Plica
- Plica Irritation Syndrome
Background
- This page refers to plica syndrome, a disease of thickened synovial lining of the Knee Joint
- Symptoms often overlap greatly with Patellofemoral Pain Syndrome
History
- First case published in 1979 by Mitel[1]
Epidemiology
- Estimated prevalence among European studies is approximately 10%[2]
- Up to 60% may be bilateral, although often not simultaneously[3]
Introduction



General
- Overuse condition characterized by irritation or inflammation of the synovial plica, most commonly the medial plica
- Patient soften report clicking, snapping or catching sensation with knee flexion and extension
- Symptoms are often worse with repetitive activities like running, squatting and climbing stairs
- Treatment is non-surgical and ocassional surgical in refractory cases with good long term outcomes
Normal Plicae
- Inward folds of the synovial lining and are present in most knees
- Normally, thin and pliable and appear almost transparent
Pathologic Plicae
- Inherent qualities change due to an inflammatory process that alters the pliability of synovial tissue
- Can become inelastic, tight, thickened, fibrotic, and sometimes hyalinized
4 Major Plica
- General
- Most important clinically
- Pathology
- May bowstring across the femoral trochlea, causing impingement between the patella and femur in knee flexion
Etiology
- Majority of cases are idiopathic
- Other proposed etiologies
- Trauma (direct, blunt)
- Twisting injuries
- Overuse injuries, especially with inadequate healing
- Repetitive flexion-extension
- Hematoma
- Diabetes Mellitus
- Inflammatory Arthropathy
- Any cause of synovitis
- Increased activity levels
Anatomy of Synovial Plicae of the Knee
- General
- Inward folds of synovial lining present in most knees
- Thin, pliable and almost transparent
- Embryologically, they form during development and are generally resorbed
- Medial Patellar Plica[7]
- Proximally, it attaches to the Articularis Genus Muscle
- Distally it inserts into the intra-articular synovial lining
- Blends into the medial patellotibial ligament on the medial aspect of the retropatellar fat pad
- Suprapatellar Plica
- From suprapatellar space, extends from the medial wall of the knee toward the lateral wall
- Infrapatellar Plica
- Also called the Ligamentum Mucosum
- Most common, resides in intercondylar notch
Risk Factors
- Systemic illness
- Diabetes Mellitus
- Inflammatory Arthropathy
Differential Diagnosis
Differential Diagnosis Knee Pain
- Fractures
- Dislocations & Subluxations
- Patellar Dislocation (and subluxation)
- Knee Dislocation
- Proximal Tibiofibular Joint Dislocation
- Muscle and Tendon Injuries
- Ligament Pathology
- Arthropathies
- Bursopathies
- Patellofemoral Pain Syndrome (PFPS)/ Anterior Knee Pain)
- Neuropathies
- Other
- Bakers Cyst (Popliteal Cyst)
- Patellar Contusion
- Pellegrini Stieda Syndrome
- Parameniscal Cyst
- Pediatric Considerations
- Patellar Apophysitis (Sinding-Larsen-Johnansson Disease)
- Patellar Pole Avulsion Fracture
- Tibial Tubercle Avulsion Fracture
- Tibial Tuberosity Apophysitis (Osgood Schalatters Disease)
- Proximal Tibial Metaphyseal Fracture
- Proximal Tibial Physeal Injury
Clinical Features


History
- Patients report anterior or anteromedial knee pain
- Other symptoms include clicking, clunking, buckling, and a popping sensation
- Often worse with squatting, jumping, stairs, standing, etc
- In pediatrics, may be associated with period of growth
Physical Exam: Physical Exam Knee
- Mild effusion can be present
- Can palpate by rolling finger over the plica fold which feels like a ribbonlike fold of tissue
- Typically found underlying the medial femoral condyle
- Medial femoral condyle may be tender
Special Tests
- Hughstons Plica Test: Knee flexed and extending while palpating medial femoral condyle
- Stutter Test: Knee extended while observing for 'stuttering' of the patella
- Plica Active Extension Test: Patient quickly, actively extends knee as in kicking a ball
- Plica Flexion Test: Patient quickly flexes knee from full extension
- Medial Patellar Plica Test: Apply inferomedial for to patella, flex and extend the knee
Evaluation


Radiographs
- Standard Radiographs Knee
- Typically normal
- Useful to exclude other causes of knee pain
Ultrasound
- Dynamic Sonography[12]
- Using arthroscopy to as gold standard
- Paczesny found Sensitivity 90%, specificity 83%, diagnostic accuracy 88%
MRI
- Findings[13]
- Hypertrophied plica as a low-intensity signal
- Often appears normal
- Better seen if joint is effused
Arthroscopy
- Remains gold standard for diagnoses
- However, not recommended strictly for diagnostic purposes as subsequent scar tissue may worsen symptoms
Classification

Ino Classification of Mediopatellar Plica
- Type A: plicae exist as a thin, cord-like elevation of the synovial wall under the retinaculum.
- Unlikely to cause symptoms
- Type B: narrow synovium with a shelf-like appearance, does not cover the anterior surface of the medial femoral condyle
- Unlikely to cause symptoms
- Type C: larger, with a shelf-like appearance that partially covers the medial femoral condyle
- Type D: similar to type C plicae, though this final type is fenestrated, splitting into two portions at its origin
Lyu and Hsu Classification of Mediopatellar Plica
- Type A plica has no direct contact with the medial femoral condyle
- Type B plica rides onto, but not beyond half of the condyle
- Type C plica covers more than half of the medial femoral condyle.
- Further subclassified into grades I-V based on thickness, degree of fibrosis
Management
Nonoperative
- General
- First line treatment in vast majority of cases
- Often directed at underlying etiology (i.e. systemic illness or other structural knee disease)
- Majority of treatment recommendations based on Patellofemoral Pain Syndrome, not necessarily specific to plica syndrome
- Activity Modification
- Modify their activities that are known to exacerbate plica syndrome
- Examples include high-impact loading such as jumping, squatting, or lunging
- Physical Therapy
- Emphasis on Quadriceps strengthening, hamstring stretching
- Decrease compressive forces in the knee
- Kinesiology Taping
- Corticosteroid Injection
Operative
- Indications
- Failure of conservative management
- Technique
- Arthroscopic resection
Rehab and Return to Play
Rehabilitation
- Phase I: Control pain/inflammation, restore ROM, gait training[15]
- Phase II: Achieve full ROM, advanced strengthening, proprioception, and cardiovascular conditioning
- Phase III: Sport-specific functional progression, tailored to the athlete’s demands
Rehab Protocol PDFs
- Medial Plica Syndrome Handout and Rehab PDF
- Plica Syndrome Rehab PDF
- Plica Syndrome Surgery Rehabilitation PDF
Return to Play
- General RTP Criteria
- Symptom resolution
- Full ROM
- Restoration of strength
- Successful functional testing
- Psychological readiness
Prognosis and Complications
Prognosis
- General
- Generally favorable with a timely diagnosis and appropriate management
- Younger patients with a shorter course of illness are more likely to respond to conservative measures[16]
- Following surgical intervention
- Long-term follow-up studies show sustained improvement in knee function and pain scores[17]
Complications
- Patellofemoral Pain Syndrome
- Knee Osteoarthritis
- Especially of the medial compartment[18]
- Inability to return to sport
- Chronic pain
- Chondromalacia Patella
- Recurrance
See Also
Internal
External
- Sports Medicine Review Knee Pain: https://www.sportsmedreview.com/by-joint/knee/
References
- ↑ Mital, Mohinder A., and John Hayden. "Pain in the knee in children: the medial plica shelf syndrome." The Orthopedic Clinics of North America 10.3 (1979): 713-722.
- ↑ Lee, Paul Yuh Feng, et al. "Synovial plica syndrome of the knee: a commonly overlooked cause of anterior knee pain." The Surgery Journal 3.1 (2017): e9.
- ↑ Dupont J Y. Synovial plicae of the knee. Controversies and review. Clin Sports Med. 1997;16(01):87–122
- ↑ Image courtesy of radsource.us
- ↑ Lee, Paul Yuh Feng, et al. "Synovial plica syndrome of the knee: a commonly overlooked cause of anterior knee pain." The Surgery Journal 3.01 (2017): e9-e16.
- ↑ Hoehmann, Christopher L. "Plica syndrome and its embryological origins." Edorium J Orthop 3 (2017): 1-12.
- ↑ Dandy D J. Anatomy of the medial suprapatellar plica and medial synovial shelf. Arthroscopy. 1990;6(02):79–85.
- ↑ Lee, Paul Yuh Feng, et al. "Synovial plica syndrome of the knee: a commonly overlooked cause of anterior knee pain." The Surgery Journal 3.01 (2017): e9-e16.
- ↑ Image courtesy of uptodate.com, "Medial patellar plica test"
- ↑ Paczesny, Łukasz, and Jacek Kruczynski. "Medial plica syndrome of the knee: diagnosis with dynamic sonography." Radiology 251.2 (2009): 439-446.
- ↑ Case courtesy of Andrew Dixon, Radiopaedia.org, rID: 18022
- ↑ Paczesny L, Kruczynski J. 2009. Medial plica syndrome of the knee: Diagnosis with dynamic sonography. Radiology 251:439–446.
- ↑ Garcia-Valtuille R, Abascal F, Cerezal I, Garcia-Valtuille A, Pereda T, Canga A, Cruz A. 2002. Anatomy and MR imaging appearances of synovial plicae of the knee. Radiographics 22:775–784.
- ↑ Image courtesy of radsource.us
- ↑ De Carlo, Mark, and Brain Armstrong. "Rehabilitation of the knee following sports injury." Clinics in sports medicine 29.1 (2010): 81-106.
- ↑ Sznajderman T, Smorgick Y, Lindner D, Beer Y, Agar G. 2009. Medial plica syndrome. Isr Med Assoc J 11:54–57.
- ↑ Prejbeanu, Radu, et al. "Long term results after arthroscopic resection of medial plicae of the knee—a prospective study." International orthopaedics 41.1 (2017): 121-125.
- ↑ Lyu SR. 2008. Arthroscopic medial release for medial compartment osteoarthritis of the knee: The result of a single surgeon series with minimum follow-up of four years. J Bone Joint Surg Br 90:1186–1192.
Created by:
John Kiel on 7 July 2019 05:31:24
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Last edited:
5 January 2026 00:25:43
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